Two FDA-approved opioid prescription drugs for severe acute pain are Nucynta (or oxycodone). These drugs are used to treat severe pain and other conditions that can’t be treated with non-opioid medication. Both pain medications can be abused or depended upon, and are therefore classified as narcotics.
It is still not clear how Nucynta functions. A few studies have revealed that Nucynta acts as a mu receptor (pain receptor agonist) and a norepinephrine receptor reuptake inhibit, which can lead to pain relief. The brain’s mu receptors are activated by Oxycodone, which blocks or weakens pain signals. This results in pain relief.
Both drugs have a very strong effect and are used when a non-narcotic pain reliever is not effective. Both drugs can be used to treat severe pain. However, there are many differences between them, which we will discuss below.
What are the main differences in Nucynta versus oxycodone
Nucynta is an opioid (or narcotic), analgesic (painkiller). You can get it in brand-name both as an immediate-release or extended-release tablet. The extended-release tablet is Nucynta EER. As needed to relieve pain, the initial dose is 50mg to 100mg every four to six hours. Your doctor may adjust the dose to suit your needs. The maximum daily dose is 600 mg.
Oxycodone can also be used as a generic opioid analgesic and oxycodone Ir, for immediate-release. It is also available in brand-name Oxycontin-a extended-release tablet. There are many dosage options, but the most common is to take 5 to 15 mg of immediate-release oxycodone tablets every four to six hours depending on how severe your pain is.
Treatments with Nucynta or oxycodone
Both oxycodone and Nucynta have one indication of treatment. This is to treat acute pain in adults who are severe enough to need an opioid analgesic.
Which is more effective, Nucynta versus oxycodone?
In a study, patients suffering from moderate to severe back pain experienced immediate-release Nucynta and immediate-release Oxycodone. Both drugs were equally safe and effective in relieving back pain. Patients who took Nucynta had fewer stomach side effects.
A study comparing abuse potential of Nucynta and oxycodone patients found that Nucynta had less potential to be abused.
Your doctor will determine the best medication for you based on your medical history and any other medications that you have taken.